How many women refuse tamoxifen

The tool does have some limits, though. For instance, it only looks at family history in close relatives like siblings, parents, and children. Other risk assessment tools, such as the Tyrer-Cuzick model and the Claus model , are based largely on family history. There is no single definition of a higher than average risk of breast cancer. But most major studies have used a 1. Some medical organizations recommend that doctors discuss the use of medicines to lower breast cancer risk in women at least 35 years old who have a 5-year risk of 1.

Others might use different cutoff points. The American Cancer Society does not have recommendations for the use of medicines to help lower the risk of breast cancer. All drugs have risks and side effects that must be discussed when making the decision about chemoprevention.

Retrieved November 14, from www. The study suggests that However, some treatment options put these women at greater risk for a number of other Triple-negative breast cancers, which comprise 15 to 20 percent of all breast tumors, are a particularly deadly type of ScienceDaily shares links with sites in the TrendMD network and earns revenue from third-party advertisers, where indicated.

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Close Close Alert. I will admit that I am shocked by this report from the UK that six in seven women who are at high risk for breast cancer refuse to take Tamoxifen. From my perspective in Cancer World. Meaning, it is smart to do anything to avoid a cancer diagnosis. We know that it is possible due to genetic testing to identify women with carry a gene mutation usually BRCA1 or BRCA2 and are at high risk for developing breast cancer.

We also know that there are women whose genetic tests are negative, but who have a very strong family history, and they, too, are likely to be at high risk. The given reasons in the study are a belief that cancer is random and up to fate, a general distrust of medicines, and a worry about side effects.